代表性文章
徐建青团队
1. Xiaoyu Sun, Chunyan Yi, Yuanfei Zhu, Longfei Ding, Shuai Xia, Xingchen Chen, Mu Liu, Chenjian Gu, Xiao Lu, Yadong Fu, Shuangfeng Chen, Tianlong Zhang,Yaguang Zhang, Zhuo Yang, Liyan Ma, Wangpeng Gu, Gaowei Hu, Shujuan Du, Renhong Yan, Weihui Fu, Songhua Yuan, Chenli Qiu, Chen Zhao, Xiaoyan Zhang, Yonghui He, Aidong Qu, Xu Zhou, Xiuling Li, Gary Wong, Qiang Deng, Qiang Zhou, Hongzhou Lu, Zhiyang Ling*, Jianping Ding*, Lu Lu*, Xu J*, Youhua Xie* and Bing Sun* . Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nature Microbiology, 2022, in press.
2. Wang Y, Tian Q, Hao Y, Yao W, Lu J, Chen C, Chen X, Lin Y, Huang Q, Xu L, Hu J, Lei S, Wei Z, Luo Y, Li Z, Hu L, Tang J, Wu Q, Zhou X, Wu Y, Yin Z*, Xu J*, Ye L*. The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis. Nat Immunol. 2022 Feb;23(2):303-317. doi: 10.1038/s41590-021-01090-1.
3. Jian Chen, Jun Fan, Zhilu Chen, Miaomiao Zhang, Haoran Peng, Jian Liu, Longfei Ding, Mingbin Liu, Chen Zhao, Ping Zhao *, Shuye Zhang,*, Xiaoyan Zhang*, Xu J*. Nonmuscle myosin heavy chain IIA facilitate SARS-CoV-2 infection in human pulmonary cells. PNAS, 2021, 118: No. 00 e2111011118. https://doi.org/10.1073/pnas.2111011118.
4. Wang Y, Qian G, Zhu L, Zhao Z, Liu Y, Han W, Zhang X, Zhang Y, Xiong T, Zeng H, Yu X, Yu X, Zhang X, Xu J*, Zou Q*, Yan D*. HIV-1 Vif suppresses antiviral immunity by targeting STING. Cell Mol Immunol. 2022 Jan;19(1):108-121. doi: 10.1038/s41423-021-00802-9. (IF=11.5)
5. Huan He#, Qibin Liao#, Cuisong Zhu, Meiqi Feng, Lang Jiang, Zhuoqun Liu, Xiangqing Ding, Xiaoyan Zhang*, Jianqing Xu*. Conditioned CAR-T Cells by Hypoxia-inducible Transcription Amplification (HiTA) System Significantly Enhances Systemic Safety and Retains Anti-tumor Efficacy. J Immunother Cancer. 2021 Oct; 9(10):e002755. doi: 10.1136/jitc-2021-002755. (IF=13.75)
6. Huang L, Ding L, Zhou J, Chen S, Chen F, Zhao C, Xu J*, Hu W*, Ji J*, Xu H*, Liu GL*. One-step rapid quantification of SARS-CoV-2 virus particles via low-cost nanoplasmonic sensors in generic microplate reader and point-of-care device. Biosens Bioelectron (IF=10.618). 2021 Jan 1;171:112685. doi: 10.1016/j.bios.2020.112685.
7. Chen T, Ding X, Liao Q, Gao N, Chen Y, Zhao C*, Zhang X*, Xu J*. IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. J Immunother Cancer (IF=13.75). 2021 Jan;9(1): e001647. doi: 10.1136/jitc-2020-001647.
8. Srivastava M, Zhang Y, Chen J, Sirohi D, Miller A, Zhang Y, Chen Z, Lu H, Xu J*, Kuhn RJ*, Andy Tao W*. Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor. Nat Commun (IF=14.919). 2020; 11(1):3896. doi: 10.1038/s41467-020-17638-y.
9. Wan J, Xing S, Ding L, Wang Y, Gu C, Wu Y, Rong B, Li C, Wang S, Chen K, He C, Zhu D, Yuan S, Qiu C, Zhao C, Nie L, Gao Z, Jiao J, Zhang X, Wang X, Ying T, Wang H, Xie Y, Lu Y, Xu J*, Lan F*. Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection. Cell Rep (IF=9.423). 2020 Jul 21;32(3):107918. doi: 10.1016/j.celrep.2020.107918.
10. Fu W, Liu Y, Liu L, Hu H, Cheng X, Liu P, Song Z, Zha L, Bai S, Xu T, Yuan S, Lu F, Shang Z, Zhao Y, Wang J, Zhao J, Ding L, Chen J, Zhang L, Zhu T*, Zhang X*, Lu H*, Xu J*. An open-label, randomized trial of the combination of IFN-κ plus TFF2 with standard care in the treatment of patients with moderate COVID-19. EClinicalMedicine （Lancet group）. 2020. 27:100547. doi: 10.1016/j.eclinm.2020.100547. （Web feature article）
11. He Y, Fu W, Cao K, He Q, Ding X, Chen J, Zhu L, Chen T, Ding L, Yang Y, Zhu C, Yuan S, Li Z, Zhao C, Zhang X*, Xu J*. IFN-κ suppresses the replication of influenza A viruses through the IFNAR-MAPK-Fos-CHD6 axis. Sci Signaling （IF=8.192）. 2020. 13: eaaz3381. doi: 10.1126/scisignal.aaz3381. （封面文章）
12. Chen J, Chen Z, Liu M, Qiu T, Feng D, Zhao C, Zhang S*, Zhang X*, Xu J*. Placental Alkaline Phosphatase Promotes Zika Virus Replication by Stabilizing Viral Proteins through BIP. mBio （IF=7.867）. 2020. 11: e01716-20. doi: 10.1128/mBio.01716-20. （编辑推荐）
13. Zhang W, Xu L, Park HB, Hwang J, Kwak M, Lee PCW, Liang G, Zhang X, Xu J, Jin JO*. Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy. Nat Communication. 2020; 11:1187. doi: 10.1038/s41467-020-15030-4.
14. Qiu T, Yang Y, Qiu J, Huang Y, Xu T, Xiao H, Wu D, Zhang Q, Zhou C, Zhang X, Tang K, Xu J*, Cao Z*. CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens. Nature Communication, 2018, 9(1): 1772
15. Wang Z, Zhu L, Nguyen T, Wan Y, Sant S, Quiñones-Parra S, Crawford J, Eltahla A, Rizzetto S, Bull R, Qiu C, Koutsakos M, Clemens B, Loh L, Chen T, Liu L, Cao P, Ren Y, Kedzierski L, Kotsimbos T, McCaw J, Gruta N, Turner S, Cheng A, Luciani F, Zhang X, Doherty P, Thomas P, Xu J* and Kedzierska K* Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease. Nature Communication, 2018, 9: 824
16. Jian Chen, Yi-feng Yang, Yu Yang, Peng Zou, Jun Chen, Yongquan He, Sai-lan Shui, Yan-ru Cui, Ru Bai, Ya-jun Liang, Yunwen Hu, Biao Jiang, Lu Lu, Xiaoyan Zhang*, Jia Liu*, Xu J*. AXL Promotes Zika Virus Infection in Astrocytes by Antagonizing Type I Interferon Signaling. Nature Microbiology （IF=17.745）, 2018, 3(3): 302-309. doi: 10.1038/s41564-017-0092-4.
17. Zhao C*, Xu J*. Toward universal influenza virus vaccines: from natural infection to vaccination strategy. Curr Opin Immunol (IF=7.486). 2018，53:1-6.
18. Ran He, Shiyue Hou, Cheng Liu, Anli Zhang, Qiang Bai, Miao Han, Yu Yang, Gang Wei, Ting Shen, Xinxin Yang, Lifan Xu, Xiangyu Chen, Yaxing Hao, Chuhong Zhu, Juanjuan Ou, Houjie Liang, Ting Ni, Xiaoyan Zhang, Xinyuan Zhou, Xu J, Hai Qi*, Yuzhang Wu* and Lilin Ye*. Follicular CXCR5-expressing CD8 T cells curtail chronic viral infection. Nature, 2016, 537 (7620):412-428. doi: 10.1038/nature19317. （Provided HIV data）
19. Liyen Loh, Zhongfang Wang, Sneha Sant, Marios Koutsakos, Sinthujan Jegaskanda, Alexandra J Corbett, Ligong Liu, David P Fairlie, Jane Crowe, Jamie Rossjohn, Xu J, Peter C Doherty, James McCluskey, Katherine Kedzierska. Human mucosal-associated invariant T cells contribute to anti-viral influenza immunity via IL-18 dependent activation. PNAS, 2016; 113(36):10133-8. doi: 10.1073/pnas.1610750113.
20. Wang Z, Wan Y, Qiu C, Quiñones-Parra S, Zhu Z, Loh L, Tian D, Ren Y, Hu Y, Zhang X, Thomas PG, Inouye M, Doherty PC, Kedzierska K*, Xu J*. Rapid recovery from severe H7N9 disease requires a diversity of response mechanisms dominated by CD8+ T cells. Nat. Communication. 2015, 6: 6833. doi: 10.1038/ncomms7833.
21. Zhe Bao Wu, Lin Cai, Chao Qiu, An Li Zhang, Shao Jian Lin, Yu Yao, Xu J*, and Liangfu Zhou*. CTL responses to HSP47 associated with the prolonged survival of glioblastomas patients. Neurology （IF=9.910）, 2014, 82(14):1261-5.
22. Wang Z, Zhang A, Wan Y, Liu X, Qiu C, Xi X, Ren Y, Wang J, Dong Y, Bao M, Li L, Zhou M, Yuan S, Sun J, Zhu Z, Chen L, Li Q, Zhang Z, Zhang X*, Lu S, Doherty PC, Kedzierska K*, Xu J*. Early hypercytokinemia is associated with IFITM3 dysfunction and predictive of fatal H7N9 infection. PNAS （IF=11.205）, 2014, 111:769-74.
23. Qiu C, Huang Y, Wang Q, Tian D, Zhang W, Hu Y, Yuan Z, Zhang X*, Xu J*. Boosting Heterosubtypic Neutralization Antibodies in Recipients of 2009 Pandemic H1N1 Influenza Vaccine. Clinical Infectious Diseases (IF=9.079), 2012. 54: 17-24. （2015 IF=8.88, 5-Year IF=9.2）
24. Yong Qiao, Yang Huang, Chao Qiu, Xinye Yue, Liandong Deng, Yanmin Wan, Jinfeng Xing, Congyou Zhang, Songhua Yuan, Anjie Dong*, Xu J*. The Use of PEGylated Poly [2-(N, N-dimethylamino) ethyl methacrylate] as A Mucosal DNA Delivery Vector and the Activation of Innate Immunity and Improvement of HIV-1-specific Immune Responses. Biomaterials （IF=12.479）, 31 (2010)： 115–123.
25. Liu, S., C. Qiu, R. Miao, J. Zhou, W. Fu, L. Zhu, L. Zhang, Xu J, M. Fu, and T. Wang. 2013. MCPIP1 restricts HIV infection and is rapidly degraded in activated CD4+ T cells. PNAS 2013;110(47):19083-8. doi: 10.1073/pnas.1316208110.
26. Lori F, Lewis M, Xu J, Varga G, Zinn D, Crabbs C, Wagner W, Greenhouse J, Silvera P, Yalley-Ogunro J, Tinelli C & Lisziewicz J. Control of SIV rebound through structured treatment interruptions during early infection. Science, 290: 1591~93, 2000. （The major postdoc to take this project）
张晓燕团队
1. Yunyu Mao#, Qibin Liao#, Youwei Zhu#, Mingyuan Bi#, Jun Zou#, Nairong Zheng, Lingyan Zhu, Chen Zhao, Qing Liu, Li Liu, Jun Chen, Ling Gu, Zhuoqun Liu, Xinghao Pan, Ying Xue, Meiqi Feng, Tianlei Ying, Pingyu Zhou, Zhanshuai Wu, Jian Xiao, Renfang Zhang*, Jing Leng*, Yongtao Sun*, Xiaoyan Zhang*, Jianqing Xu*. Efficacy and Safety of Novel Multifunctional M10 CAR-T Cells in HIV-1-Infected Patients: A Phase I, Multicenter, Single-Arm, Open-Label Study. Cell Discovery. 10, 49 (2024). https://doi.org/10.1038/s41421-024-00658-z
2. Wang J, Cheng X, Jin Y, Xia B, Qin R, Zhang W, Hu H, Mao X, Zhou L, Yan J, Zhang X*, Xu J*, "Safety and clinical response to combined immunotherapy with autologous iNKT cells and PD-1+CD8+ T cells in patients failing first-line chemotherapy in stage IV pancreatic cancer. Cancer Research Communications,2023 Jun 7;3(6):991-1003. doi: 10.1158/2767-9764. CRC-23-0137. eCollection 2023 Jun. PMID: 37377605
3. Rongrong Gao#, Ang Li#, Sen Li, Xiangrong Li, Shuye Zhang, Xiaoyan Zhang*, Jianqing Xu*. Induced regulatory T cells modified by knocking down T-bet in combination with ectopic expression of inhibitory cytokines effectively protect Graft-versus-Host Disease. American Journal of Transplantation, 2023Jul;23(7):946-956. doi: 10.1016/j.ajt.2023.04.017.
4. Shimeng Bai, Tianhan Yang, Cuisong Zhu, Meiqi Feng, Li Zhang, Ziling Zhang, Xiang Wang, Rui Yu, Xinghao Pan, Chen Zhao*, Jianqing Xu* and Xiaoyan Zhang*. A single vaccination of nucleoside-modified Rabies mRNA vaccine induces prolonged highly protective immune responses in mice. Frontiers in Immunology-. 2023 Jan 17;13:1099991. doi: 10.3389/fimmu.2022.1099991.
5. Chenli Qiu, Jing Wang, Lingyan Zhu, Xiaobo Cheng, Bili Xia, Yanling Jin, Qin Ran, Linxia Zhang, Huiliang Hu, Jia Yan, Chen Zhao, Xiaoyan Zhang* and Jianqing Xu* Improving the ex vivo expansion of human tumor-reactive CD8 + T cells by targeting Toll-like receptors, Frontiers in Bioengineering and Biotechnology, 31 October 2022，https://doi.org/10.3389/fbioe.2022.1027619
6. Qibin Liao*, Zhuoqun Liu*, Cuisong Zhu*, Huan He*, Meiqi Feng, Lang Jiang, Xiangqing Ding, Rongxun Sun#, Xiaoyan Zhang#, Jianqing Xu#. Rapid generation of a mouse model for evaluating on-target normal tissue toxicity of human CAR-T cells using replication-defective recombinant adenovirus. Journal of Advanced Research. 2022 Aug 20:S2090-1232(22)00189-8. doi: 10.1016/j.jare.2022.08.008. PMID:35995414
7. Jing Wang*, Renfang Zhang*, Xiangqing Ding*, Yanling Jin, Ran Qin, Bili Xia, Qibin Liao, Huiliang Hu, Wei Song, Zhenyan Wang, Xiaoyan Zhang#, Jianqing Xu#. Pathologically complete remission to combination of invariant NK T cells and anti-CD20 antibody in a refractory HIV+ diffuse large B-cell lymphoma patient. Immunotherapy. 2022 Apr 20. doi: 10.2217/imt-2021-0247.
8. Xiaobo Cheng*, Jing Wang*, Chenli Qiu, Yanling Jin, Bili Xia, Ran Qin, Huiliang Hu, Jia Yan, Xiaoyan Zhang#, Jianqing Xu#. Feasibility of iNKT cell and PD-1+CD8+ T cell-based immunotherapy in patients with lung adenocarcinoma: Preliminary results of a phase I/II clinical trial. Clin Immunol. 2022 Mar 30;238:108992. doi: 10.1016/j.clim.2022.108992.
9. Jiang Lang†, Liu Lu†, Zhang Miaomiao, Zhang Linxia, Zhu Cuisong, He Qian, Ye Lilin, Zhao Chen*, Li Zejun*, Xu Jianqing*, Zhang Xiaoyan*. Prompt Antiviral Action of Pulmonary CD8+ TRM Cells Is Mediated by Rapid IFN-γ Induction and Its Downstream ISGs in the Lung. Frontiers in Immunology. 2022. https://www.frontiersin.org/article/10.3389/fimmu.2022.839455
10. Jian Chen#, Jun Fan#, Zhilu Chen#, Miaomiao Zhang#, Haoran Peng#, Jian Liu, Longfei Ding, Mingbin Liu, Chen Zhao, Ping Zhao*, Shuye Zhang*, Xiaoyan Zhang*, Jianqing Xu*. Nonmuscle myosin heavy chain IIA facilitates SARS-CoV-2 infection in human pulmonary cells. Proc. Natl Acad. Sci. USA. 2021 Dec 14;118(50): e2111011118.
11. Xiangchuan He#, Longfei Ding#, Kangli Cao#, Haoran Peng#, Chenjian Gu, Yutang Li, Duoduo Li, Lanlan Dong, Xiujing Hong, Xiangwei Wang, Meilan Fu, Chenli Qiu, Cuisong Zhu, Ziling Zhang, Shu Song, Chenguang Wang, Zhengfan Jiang, Youhua Xie, Zhongtian Qi, Chen Zhao*, Ping Zhao*, Xiaoyan Zhang*, Jianqing Xu*. A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge. Emerging Microbes & Infections. 2021,10(1):1555-1573.
12. Huan He#, Qibin Liao#,Chen Zhao,Cuisong Zhu,Meiqi Feng,Zhuoqun Liu,Lang Jiang,Linxia Zhang,Xiangqing Ding,Min Yuan*,Xiaoyan Zhang, Jianqing Xu*. Conditioned CAR-T cells by hypoxia-inducible transcription amplification (HiTA) system significantly enhances systemic safety and retains antitumor efficacy. Journal for ImmunoTherapy of Cancer. 2021 Oct;9 (10) : e002755. doi: 10.1136/jitc-2021-002755.
13. Tianyue Chen#, XiangqingDing#, Qibin Liao, Nan Gao, Ye Chen, Chen Zhao*, Xiaoyan Zhang*, JianqingXu*. IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy. Journal for ImmunoTherapy of Cancer. 2021 Jan;9(1):e001647.doi: 10.1136/jitc-2020-001647.
14. Ang Li#, Yun Lin#, Zhigang Song#, Xiaobo Cheng, Weihui Fu, Yan Liu, Huiliang Hu, Songhua Yuan, Jian Chen, Jun Fan, Min Wang, Jing Wang, Yanling Jin, Miaomiao Zhang, Lingyan Zhu, Peng Sun, Linxia Zhang, Ran Qin, Wei Zhang, Chenli Qiu, Yinzhong Shen, Lin Zhang, Tongyu Zhu*, Hongzhou Lu*, Xiaoyan Zhang*, Jianqing Xu1*.Early plasma IL-37 responses accompanied with low inflammatory cytokines correlate with benign clinical outcomes during SARS-CoV-2 infection. The Journal of Infectious Diseases, 2020 Nov 17:jiaa713. doi: 10.1093/infdis/jiaa713.
15. Qibin Liao, Yunyu Mao, Huan He, Xiangqing Ding, Xiaoyan Zhang*, Jianqing Xu* . PD-L1 chimeric costimulatory receptor improves the efficacy of CAR-T cells for PD-L1-positive solid tumors and reduces toxicity in vivo. Biomark Res, 2020 Nov 2;8(1):57. doi: 10.1186/s40364-020-00237-w. PMID: 33292688; PMCID: PMC7607631.
16. Qibin Liao#, Huan He#, Yunyu Mao, Xiangqing Ding, Xiaoyan Zhang*, Jianqing Xu*. Engineering T cells with hypoxia-inducible chimeric antigen receptor (HiCAR) for selective tumor killing. Biomark Res, 2020. 8: 56. doi: 10.1186/s40364-020-00238-9.
17. Qian He , Lang Jiang, Kangli Cao, Linxia Zhang, Xinci Xie, Shuye Zhang, Xiangqing Ding, Yongquan He, Miaomiao Zhang, Tianyi Qiu, Xuanxuan Jin, Chen Zhao*, Xiaoyan Zhang*, Jianqing Xu*. A Systemic Prime-Intrarectal Pull Strategy Raises Rectum-Resident CD8+ T Cells for Effective Protection in a Murine Model of LM-OVA Infection. Frontiers in Immunology. 2020 Sep 24;11:571248.doi: 10.3389/ fimmu. 2020.571248. eCollection 2020.
18. Chen J#, Chen Z#, Liu M, Qiu T ,Zhao C, Zhang S*, Zhang X*,Xu J*. Placental alkaline phosphatase promotes Zika virus replication by stabilizing viral proteins through BIP. mBio. 2020. 11: e01716-20. doi: 10.1128/mBio.01716-20.
19. Linxia Zhang†, Anli Zhang†, Jun Xu†, Chao Qiu, Lingyan Zhu, Chenli Qiu, Weihui Fu, Ying Wang, Lilin Ye, YangXin Fu, Chen Zhao*, Xiaoyan Zhang*, Jianqing Xu*. CD160 plays a protective role during chronic infection by enhancing both functionalities and proliferative capacity of CD8+ T cells. Frontiers in Immunology 11, 10.3389/fimmu.2020.02188
20. Weihui Fu, Yan Liu, Li Liu, Huiliang Hu; Xiaobo Cheng, Ping Liu; Zhigang Song; Lijun Zha; Shimeng Bai; Tingting Xu; Songhua Yuan; Fengru Lu; Zhiying Shang; Yihong Zhao; Jing Wang, Jun Zhao; Longfei Ding; Jun Chen, Lin Zhang; Tongyu Zhu*, Xiaoyan Zhang*, Hongzhou Lu*, Jianqing Xu*. An open-label, randomized trial of the combination of IFN-κ plus TFF2 with standard care in the treatment of patients with moderate COVID-19. E Clinical Medicine. 2020 Oct;27:100547.doi: 10.1016/j.eclinm.2020.100547（Web feature article）.
21. Yongquan He, Weihui Fu, Kangli Cao, Qian He, Xiangqing Ding , Jian Chen , Lingyan Zhu, Tianyue Chen, Longfei Ding, Yu Yang，Cuisong Zhu, Songhua Yuan, Zejun Li, Chen Zhao*, Xiaoyan Zhang*, Jianqing Xu*. IFN-κ suppresses the replication of influenza A virus through IFNAR-MAPK-Fos-CHD6 axis. Science Signaling， 7 April 2020. 13(626): eaaz3381. doi: 10.1126/scisignal.aaz3381.
22. Jian Chen#, Yi-feng Yang#, Yu Yang, Peng Zou, Yongquan He, Sai-lan Shui, Jun Chen, Ru Bai, Ya-jun Liang, Yunwen Hu, Biao Jiang, Lu Lu, Xiaoyan Zhang*, Jia Liu*, Jianqing Xu*. AXL Promotes Zika Virus Infection in Astrocytes by Antagonizing Type I Interferon Signaling Pathway. Nature microbiology. 2018 Jan 29. 3: 302–309.
23. Shan Jin, Qibin Liao, Jian Chen, Linxia Zhang, Qian He, Huanzhang Zhu, Xiaoyan Zhang*，Jianqing Xu* .TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway. Emerging Microbes & Infections. 138 (2018)：https://doi.org/10.1038/s41426 -018-0139-5.
24. Hillary A Vanderven#, Lu Liu#, Fernanda Ana-Sosa-Batiz, Thi HO Nguyen, Yanmin Wan, Bruce Wines, P Mark Hogarth, Danielle Tilmanis, Arnold Reynaldi, Matthew S Parsons, Aeron C Hurt, Miles P Davenport, Tom Kotsimbos, Allen C Cheng, Katherine Kedzierska, Xiaoyan Zhang*, Jianqing Xu* and Stephen J Kent* Fc functional antibodies during severe human H7N9 and seasonal influenza. JCI Insight 2017; 2(13): e92750. https://doi.org/10.1172/jci.insight.92750.
25. Liu L#, Nachbagauer R#, Zhu L, Huang Y, Xie X, Jin S, Zhang A, Wan Y, Hirsh A, Tian D, Shi X, Dong Z, Yuan S, Hu Y, Krammer F*, Zhang X*, Xu J*. Induction of Broadly Cross-Reactive Stalk-Specific Antibody Responses to Influenza Group 1 and Group 2 Hemagglutinins by Natural H7N9 Virus Infection in Human. J Infect Dis. 2017 Feb 15;215(4):518-528. doi: 10.1093/infdis/jiw608.
26. Yu Yang, Jingyu Zhu, Matthew Hassink, Lisa M. Miller Jenkins, Yanmin Wan, Daniel H. Appella, Jianqing Xu, Ettore Appella,*, Xiaoyan Zhang,* A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion. Emerging Microbes & Infections. 2017. Jun 7;6(6):e40. doi: 10.1038/emi.2017.26.
27. Jun Huang, Lingyan Zhu, Chao Qiu, Xuan Xu, Linxia Zhang, Xiangqing Ding, Qibin Liao, Jianqing Xu*, Xiaoyan Zhang*. MiR-126-5p enhances the inflammatory response of monocytes to LPS through suppressing CYLD in chronic HIV-1 infection. Journal of Virology. 2017 Mar 1. pii: JVI.02048-16. doi: 10.1128/JVI.02048-16.
28. Qibin Liao; Jin Wang; Zenglin Pei; Jianqing Xu; Xiaoyan Zhang*. Identification of miRNA-mRNA crosstalk in CD4+ T cells during HIV-1 infection by integrating transcriptome analyses. Journal of Translational Medicine. 2017Feb 21;15(1):41. doi: 10.1186/s12967-017-1130-y.
29. Weihui Fu, Chao Qiu*, Mingzhe Zhou, Lingyan Zhu,Yu Yang, Chenli Qiu, Linxia Zhang, Xuan Xu, Jun Sun, Jun Wei, Ying Wang*, Jianqing Xu, Xiaoyan Zhang*. Dictating SAMHD1 in CD4+T Lymphocyte and Monocyte by Immune Activation during Chronic HIV-1 Infection. Scientific Reports. 6:38162. doi: 10.1038/srep38162. 2016.
30. Miaomiao Zhang, Xingxing Zhang, Kaidi Xu, Qiaoyang Teng, Qinfang Liu, Xuesong Li, Jianmei Yang, Jianqing Xu, Hongjun Chen*, Xiaoyan Zhang*, and Zejun Li*. Characterization of the Pathogenesis of H10N3, H10N7, and H10N8 Subtype Avian Influenza Viruses Circulating in Ducks. Scientific Reports. 2016; 6 : 34489.
31. Ren Y, Li L, Wan Y, Wang W, Wang J, Chen J, Wei Q, Qin C, Xu J, Zhang X*. Mucosal topical microbicide candidates exert influence on the subsequent SIV infection and survival by regulating SIV-specific T cell immune responses. Journal of Acquired Immune Deficiency Syndromes. 2016 Feb 1; 71(2):121-9.
32. Xiaoling Tian, Anli Zhang, Chao Qiu, Wei Wang, Yu Yang, Chenli Qiu, Aiping Liu, Linyan Zhu, Songhua Yuan, Huiliang Hu, Wanhai Wang, Qiang Wei, Xiaoyan Zhang* and Jianqing Xu. The Upregulation of LAG-3 on T Cells Defines a Subpopulation with Functional Exhaustion and Correlateswith Disease Progression in HIV-Infected Subjects. The Journal of Immunology, 2015, Apr 15; 194 (8): 3873-82.
33. Yuan Dong，Chao Qiu, Xueshan Xia, Jing Wang，Haiyan Zhang，Xiaoyan Zhang*, Jianqing Xu. Hepatitis B virus and hepatitis C virus infection among HIV-1 infected injection drug users in Dali, China: prevalence and infection statuses in a cross sectional study. Archives of Virology. 2015.160 (4)：929-936.
34. Aiping Liu, Yu Yang, Lu Liu, Zhefeng Meng, Liangzhu Li, Chao Qiu, Jianqing Xu, Xiaoyan Zhang*. Differential compartmentalization of HIV-targeting immune cells in inner and outer foreskin tissue. PLOS ONE (2014) 9(1): e85176.
35. Chao Qiu, Songhua Yuan, Di Tian, Qingguo Chen, Zhigang Song, Anli Zhang, Yu Yang, Yanmin Wan, Jing He, Liangzhu Li, Jun Sun, Mingzhe Zhou, Chenli Qiu, Zhiyong Zhang, Xiaoyan Zhang*, Shuihua Lu, Yunwen Hu, Jianqing Xu. Epidemiologic Report and Serologic Findings for Household Contacts of Three Cases of Influenza A (H7N9) Virus Infection. Journal of Clinical Virology 2014.59. 129-131.
36. Zhongfang Wang , Anli Zhang , Yanmin Wan , Xinian Liu , Chao Qiu , Xiuhong Xi , Yanqin Ren , Jing Wang , Yuan Dong , Meijuan Bao , Liangzhu Li , Mingzhe Zhou , Songhua Yuan , Jun Sun , Zhaoqin Zhu , Liang Chen , Qingsheng Li , Zhiyong Zhang , Xiaoyan Zhang* , Shuihua Lu , Peter C Doherty, Katherine Kedzierska , Jianqing Xu. Early hypercytokinemia is associated with IFITM3 dysfunction and predictive of fatal H7N9 infection. Proc Natl Acad Sci U S A. 2014 Jan 14; 111 (2): 769-74.
37. Liangzhu Li, Yinyin Ben, Songhua Yuan, Aiping Liu, Huanmei Wu, Jianqing Xu, Xiaoyan Zhang*. Recruitment of HIV-1 Target Cells at Topical Mucosal Site: a Sensitive and Early Marker for Determining Safety of Microbicide Candidates. Emerging Microbes and Infections (EMI). 2013. 2, e42; doi:10.1038.
38. Xing M, Hu G, Wang X, Wang Y, He F, Dai W, Wang X, Niu Y, Liu J, Liu H, Zhang X, Xu J, Cai Q, Zhou D. An intranasal combination vaccine induces systemic and mucosal immunity against COVID-19 and influenza. NPJ Vaccines. 2024 Mar 21;9(1):64. doi: 10.1038/s41541-024-00857-5. PMID: 38509167; PMCID: PMC10954707.
39. Lin M, Cao K, Xu F, Wu X, Shen Y, Lu S, Kuang Z, Ding H, Yuan S, Shao M, Gu G, Xing L, Gu T, Chen S, Sun J, Zhu J, Zhang X, Yang Y, Zhao G, Huang L, Xu J, Song Z. A follow-up study on the recovery and reinfection of Omicron COVID-19 patients in Shanghai, China. Emerg Microbes Infect. 2023 Sep 21:2261559. doi: 10.1080/22221751.2023.2261559. Epub ahead of print. PMID: 37732336.
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